General Hotkeys
| No. | Hotkey | Action Performed |
| 1 | F1 | Civilopedia |
| 2 | F2 | Economic info |
| 3 | F3 | Military info |
| 4 | F4 | Diplomacy info |
| 5 | F5 | Social Policies Screen |
| 6 | F6 | Tech Screen |
| 7 | F7 | Notification Log |
| 8 | F8 | Victory Progress |
| 9 | F9 | Demographics |
| 10 | F10 | Strategic View |
| 11 | F11 | Quick Save |
| 12 | F12 | Quick Load |
| 13 | G | Hex Grid |
| 14 | Esc | Menu |
| 15 | Enter | End Turn |
| 16 | Period | Next Unit |
| 17 | Comma | Previous Unit |
| 18 | - | Zoom Out |
| 19 | + | Zoom in |
| 20 | Insert | Capital City View |
| 21 | Home | Capital City View |
| 22 | End | Capital City View |
| 23 | Page up | Zoom in |
| 24 | Page Down | Zoom Out |
| 25 | Ctrl+R | Show Resources Icons |
| 26 | Ctrl+Y | Yield Icons |
| 27 | Ctrl+O | Game Options |
| 28 | Ctrl+S | Save |
| 29 | Ctrl+L | Load |
| 30 | Ctrl+Spcae | End Turn |
General Unit Hotkeys
| No. | Hotkey | Action Performed |
| 1 | M | Move Mode |
| 2 | E | Explore (Automated) |
| 3 | A | Alert |
| 4 | F | Sleep |
| 5 | Space | Do Nothing |
Action Hotkeys
| No. | Hotkey | Action Performed |
| 1 | Delete | Delete Unit |
| 2 | Ctrl+A | Attack |
| 3 | Ctrl+B | Ranged |
| 4 | S | Set up Artillery |
| 5 | H | Fortify Until Healed |
Air Unit Hotkeys
| No | Hotkey | Action Performed |
| 1 | Alt+R | Rebase Mode |
| 2 | S | Air Strike Mode |
| 3 | Alt+S | Air Sweep |
| 4 | I | Intercept |
| 5 | N | Nuke Mode |
Civilian Unit Hotkeys
| No. | Hotkey | Action Performed |
| 1 | B | Found City |
| 2 | A | Build Improvements (automated) |
| 3 | R | Construct a Railroad |
| 4 | R | Construct a Road |
| 5 | Alt+R | Route to Mode |
| 6 | Alt+C | Remove a Jungle |
| 7 | Alt+C | Clear a Marsh |
| 8 | T | Construct a Trading Post |
| 9 | H | Construct a Camp |
| 10 | I | Construct a Farm |
| 11 | N | Construct a Mine |
| 12 | P | Construct a Plantation |
| 13 | Q | Construct a Quarry |
| 14 | P | Construct a Pasture |
| 15 | F | Construct a Fort |
| 16 | O | Create a Well |
| 17 | F | Create Fishing Boats |
| 18 | O | Create Offshore Platform |
| 19 | Alt+C | Remove Forest |
| 20 | Backspace | Cancel Last Mission |
| 21 | L | Construct a Lumber Mill |
| 22 | C | Citadel |
Civilization V Keyboard Shortcuts and Hotkeys List